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На American Stroke Association International Stroke Conference 2010 [Ссылки доступны только зарегистрированным пользователям ] результаты CREST (Carotid Revascularization Endarterectomy Versus Stenting Trial) - самого крупного исследования, сравнивавшего CAS и CEA для предотвращения инсульта при асимптомных и симтоматических стенозах каротидных артерий.

The study included 1321 symptomatic and 1181 asymptomatic patients from 117 centers in the US and Canada, who were randomized to receive either stenting using the same stent and distal-protection devices (Acculink and Accunet, Abbott Vascular, Redwood City, CA) or carotid endarterectomy. Subjects were 35% female, and only 9.3% were minorities.
Patients with symptomatic stenosis had a >50% stenosis by angiography, >70% by ultrasound, or >70% on computed tomography/magnetic resonance angiography (CT/MRA). Asymptomatic patients had lesions >60% by angiography, >70% by ultrasound, or >80% on CT/MRA.

CAS и CEA показали сходные результаты по безопасности и эффективности.

On the composite primary end point of any stroke, MI, or death during the periprocedural period or ipsilateral stroke on follow-up, stenting was associated with a 7.2% rate of these events vs 6.8% with surgery, a nonsignificant difference.
However, individual risks varied, they found. At 30 days, the rate of stroke was significantly higher with stenting, at 4.1% vs 2.3% with surgery. Major stroke, though, was not different, at less than 1% in both groups. Conversely, MI was higher with carotid endarterectomy, at 2.3% vs 1.1% with stenting, again a statistically significant difference.
Patients who had an MI, however, reported a better quality of life after recovery than those who had a stroke, the authors noted.
Rates of ipsilateral stroke during a mean follow-up of 2.5 years were equal between groups, at 2.0% for stenting and 2.4% with surgery.