В целом заключение дают довольно сдержанное (да простит меня Martin I Surks, MD, за цитирование маленького кусочка публикации Lithium and the thyroid):
Цитата:
Because of its ability to inhibit thyroid secretion, lithium has been used in the treatment of several thyroid diseases. However, it is not used as first-line therapy, because of side effects and the availability of other antithyroid drugs (eg, thionamides).
Hyperthyroidism — Lithium (in a dose of 600 to 1000 mg/day) is effective therapy for patients with hyperthyroidism. Its effects on thyroid hormone secretion are quantitatively similar to those of iodide, and it therefore may be given in place of iodide in patients who would benefit from rapid correction of hyperthyroidism but are allergic to iodine ... It also may be useful in patients with intolerance to thionamides.
Lithium alone has been used to prepare patients for thyroidectomy [Lithium in the preoperative preparation of Graves' disease. Takami H Int Surg. 1994;79(1):89.; Successful preoperative preparation for thyroidectomy in Graves' disease using lithium alone: report of two cases. Mochinaga N, Eto T, Maekawa Y, Tsunoda T, Kanematsu T, Izumi M Surg Today. 1994;24(5):464]. This treatment led to a decrease in serum thyroid hormone concentrations and clinical improvement; subsequent surgery was successful.
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