Men taking metformin were more likely to have offspring with birth defects, a Danish study found.
Newborns with fathers who took metformin during the development of fertilizing sperm had a 40% higher frequency of birth defects compared with newborns whose fathers used insulin (adjusted OR 1.40, 95% CI 1.08-1.82), reported Maarten J. Wensink, MD, PhD, of the University of Southern Denmark, and colleagues.
The same did not hold true for offspring with fathers who took sulfonylureas versus insulin (aOR 1.34, 95% CI 0.94-1.92), they pointed out in the Annals of Internal Medicine.
Неприятно... Мб, что-то не так посчитали?
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