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Сообщение от Light
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По моему одной AACE достаточно, вот выдержка с их сайта:
"...The effects of GH and IGF-I on muscle and
bone metabolism seem to be synergistic. Both hormones
increase muscle mass, activate bone remodeling units, and
improve bone density. Although IGF-I in serum is predominantly
of hepatic origin (85%)....."
"...The term
“somatopause” has been used by some investigators to
suggest that normal aging is associated with a gradual
decline in secretion of GH accompanied by a decrease in
bone mass and lean body mass as well as an increase in
adipose mass..."
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"...In aging men, GH secretion declines by 50% every 7 years
after age 18-25 years...."
[
Ссылки доступны только зарегистрированным пользователям ] growth-hormone-replacement-in-older-men.htm
"...GH in circulation acts on many tissues and organs.
One of the main tasks of GH is to increase the production
of a substance by the liver, called Insulin-like Growth
Factor-I (IGF-I). Circulating IGF-I levels undergo important
age-related variations increasing at puberty and decreasing,
thereafter, to low levels in the elderly. Low IGF-I levels
in the elderly mainly reflect impaired GH secretion but the
decline in gonadal sex steroid levels, and malnutrition may
also play a role in the age-related decrease in IGF-I activity.
This, in turn, partially accounts for age-related changes in
bones, muscles, cardiovascular system, central nervous system
and the immune system...."
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