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According to the published data,
chemotherapy as adjuvant therapy for clinical
stage I seminoma (Table 4) provides a valid
alternative to radiotherapy. A number of
therapeutic regimens have been described
that differ with regard to the dosage [21] and
number of cycles (one or two),,,,,

In conclusion, in patients with clinical stage I
seminoma of the testis, two cycles of
carboplatin monotherapy comprises an
oncologically effective and well tolerated
treatment modality. Despite the lack of a
randomized trial, the data available in the
literature suggest that the administration of
two cycles instead of one cycle could lead to a
reduction in recurrence rates of ≈50%. Long
term follow-up of the contralateral testicle is
recommended.

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