[Samitin]

Management of Hypoglycemia in Nondiabetic Palliative Care Patients: A Prognosis-Based Approach - Palliat Care. 2016; 10: 1–5. ([Ссылки доступны только зарегистрированным пользователям ]):

In nondiabetic palliative care patients, hypoglycemia occurs most commonly in response to multiorgan dysfunctions or failures. As mentioned earlier, the prevalence of hypoglycemia in nondiabetic patients related to critical illness is not well documented. Organ failure will result in a reduction of endogenous glucose production, and most critical illnesses increase metabolic stress, thereby increasing glucose utilization by tissues. Inadequate oral intake, along with the insufficient production of glucose during a severe illness, may increase the risk of hypoglycemia. Hepatic or renal failure may result in hypoglycemia if the patient develops anorexia, vomiting, and inadequate oral intake and has impaired hepatic or renal gluconeogenesis. Hepatic failure impairs both hepatic gluconeogenesis and the glycogenolysis counterregulatory response, cutting off the regular supply of glucose required to maintain adequate plasma levels. Not only in frank liver failure setting, but hypoglycemia is also associated with increased mortality in patients with acute decompensated liver cirrhosis. In this setting, it is not yet clear whether hypoglycemia is jointly responsible for the increased short-term mortality or is only a consequence of the severity of the disease or the complications.7

To make the scenario worse, multiorgan failures can trigger endocrine organ dysfunctions, such as adrenal or pituitary gland dysfunction, fueling the risk of developing hypoglycemia.

Сведения о частоте гипогликемий достаточно примечательны.