О ПГА я речи и не веду... Хочется понять, откуда высокий ренин. Если это все следствие приема сартанов и ГХТ, а бета-блоки не воздействуют на ЮГА, то пусть так и будет.
Цитата:
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This is responsible for the two‐ to threefold increase in renin on standing and exercise, and (through their activation of the baroreceptor) for part of the increase of CCBs and α blockade. The adrenergic receptor on the JGA is the β1 adrenoceptor—one of the few extracardiac sites of the β1‐subtype—and is coupled to cyclic AMP production, through a specific isoform of adenylate cyclase (type 6).18 In hypertension, the β blockers work entirely through blockade of renin secretion.19,20 Side effects due to reduction in cardiac output can be minimised by using the most β1‐selective agents and doses.
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