Кроме, ЭДТА-зависимой, все чаще можно заметить цитрат/гепарин-зависимую псевдотромбоцитопению в лаб. практике, нередко псевдотромбоцитопении супутствует и истинная, порой это не просто лаб. феномен, а сопутств. проявление какого-то заболевания, подробнее:
355 specimens with pseudo-thrombocytopenia (PTCP) were evaluated via epidemiology, identification, remedies, and platelet (PLT) count. Data showed that anticoagulants such as citrate and/or heparin-dependent PTCP (16.0%) became increasingly common, whereas ethylenediaminetetraacetic acid (EDTA)-induced PTCP (49.1%) remained the most frequent. We note that that nearly half of the patients with PTCP had veritable decreased PLT counts, even after PLT levels had been corrected. Our findings suggest that there were seasonal changes in patients with PTCP: PLT levels were higher in spring, compared with other seasons, with winter levels being the lowest. There were higher risks of PTCP for individuals with malignant neoplasms, liver diseases, infection, and hematologic disease, compared with other conditions.
---
Lab Med. 2018 Mar 21;49(2):130-133.
Spurious Thrombocytopenia in Automated Platelet Count.
Zhang L и соавт.
|