По церебролизину нашел новое РКИ:
Neuroprotective treatment with Cerebrolysin in patients with acute stroke: a randomised controlled trial. Ladurner G, Kalvach P, Moessler H.
Department of Neurology, Christian-Doppler Hospital, Salzburg, Austria. Как видите работа из Австрии, где и производят церебролизин. Так и там отписано,что применяли Ц в остром периоде инсульта в дозе 50 мл/сут . Так вот существенного влияния на течение инсульта и неврологическую симптоматику не оказал препарат. Оказал влияние на когнитивные способности. По пирацетаму есть одно РКИ Германия 1993 год при остром инсульте у гериатрических пациентов, но группа маленькая 56 пациентов. Правда не указана доза пирацетама. Результат :A total of 56 patients were enrolled, of whom 27 were given piracetam and 29 served as a control during a 28-day period. Using single photon emission computer tomography (SPECT) analysis, we observed that in 23 piracetam-treated patients (85.2%) a reduction in the area of brain regions displaying an impaired flow rate occurred ( [Formula: see text] ). Only six of placebo-treated patients (20.7%) showed an improved flow rate. Analysis of the recorded computer tomography map gave an improvement coefficient >2 (flow rate marginally or better improved) for 23 piracetam patients as compared with 5 placebo patients
Вот что нашлось в PubMed на запрос circulatory encephalopathy drug therapy.
Как видите все работы из России.
Dziak LA, Golik VA. Related Articles, Links
[Use of mildronate for the treatment of patients with circulatory encephalopathy against a background of stenosis of major arteries of the head]
Lik Sprava. 2003 Jul-Aug;(5-6):98-101. Russian.
PMID: 14618818 [PubMed - indexed for MEDLINE]
2: Geraskina LA, Suslina ZA, Foniakin AV. Related Articles, Links
[Reactivity of cerebral vessels in patients with circulatory encephalopathy, arterial hypertension and cerebral hypoperfusion risk]
Ter Arkh. 2001;73(2):43-8. Russian.
PMID: 11338853 [PubMed - indexed for MEDLINE]
3: Khavinson VKh, Morozov VG, Rybnikov VIu, Zakutskii NG. Related Articles, Links
[Cortexin effectiveness in circulatory encephalopathy]
Klin Med (Mosk). 1999;77(4):42-5. Russian.
PMID: 10356917 [PubMed - indexed for MEDLINE]
4: Ivaniv OP. Related Articles, Links
[The results of using different forms of a Ginkgo biloba extract (EGb 761) in the combined treatment of patients with circulatory encephalopathy]
Lik Sprava. 1998 Dec;(8):123-8. Ukrainian.
PMID: 10204370 [PubMed - indexed for MEDLINE]
5: Kupnovyts'ka MIu, Lushchyk UB, Herasymchuk RD, Chmyr HS, Iatsyshyn RI, Dubanovych LB. Related Articles, Links
[A new approach to the treatment of patients with circulatory encephalopathy]
Lik Sprava. 1997 Sep-Oct;(5):142-5. Ukrainian.
PMID: 9491724 [PubMed - indexed for MEDLINE]
6: Lebedeva NV, Chukhrova VA, Solov'ev OU, Nepesov RR. Related Articles, Links
[Treatment of circulatory encephalopathy with Cavinton]
Klin Med (Mosk). 1997;75(11):51-3. Russian. No abstract available.
PMID: 9490359 [PubMed - indexed for MEDLINE]
7: Rudenko AE, Lushchik UB, Dzhumik VA. Related Articles, Links
[The clinical efficacy of tanakan in patients with stage-I atherosclerotic circulatory encephalopathy]
Lik Sprava. 1997 Mar-Apr;(2):99-101. Russian. No abstract available.
PMID: 9333499 [PubMed - indexed for MEDLINE]
8: Suga T, Goto H, Yoshioka K, Hosoya T. Related Articles, Links
[A case of Iotrolan encephalopathy]
No Shinkei Geka. 1996 Nov;24(11):1051-4. Japanese.
PMID: 8934476 [PubMed - indexed for MEDLINE]
9: Harrison P, Wendon J, Williams R. Related Articles, Links
Evidence of increased guanylate cyclase activation by acetylcysteine in fulminant hepatic failure.
Hepatology. 1996 May;23(5):1067-72.
PMID: 8621135 [PubMed - indexed for MEDLINE]
10: Shapovalov VM, Podvigin AV, Opekunova GT, Storokha AA. Related Articles, Links
[The intravenous laser therapy of circulatory encephalopathy]
Voen Med Zh. 1996 Apr;317(4):30-1. Russian. No abstract available.
PMID: 8754056 [PubMed - indexed for MEDLINE]
11: Alekhin MN, Sedov VP, Botsina GI, Sidorenko BA, Nosenko EM. Related Articles, Links
[Effect of nimodipine in the diastolic function of the left ventricle in patients with essential hypertension and atherosclerotic circulatory encephalopathy]
Klin Med (Mosk). 1996;74(8):50-2. Russian. No abstract available.
PMID: 9036211 [PubMed - indexed for MEDLINE]
12: Ishchenko MM, Nechai IeO, Korol'kov OS. Related Articles, Links
[The pentoxifylline and corglycon treatment of patients with circulatory encephalopathy against a background of atherosclerotic lesions of the major cerebral arteries]
Lik Sprava. 1996 Jan-Feb;(1-2):143-5. Ukrainian.
PMID: 9005077 [PubMed - indexed for MEDLINE]
13: Shprakh VV, Molokov DD, Tatarinova MB, Burdukovskaia NL. Related Articles, Links
[Vasobral in the treatment of initial atherosclerotic circulatory encephalopathy]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1996;96(2):39-40. Russian. No abstract available.
PMID: 8754338 [PubMed - indexed for MEDLINE]
14: Grebel'nik VI. Related Articles, Links
[The efficacy of treatment with the tranquilizer tranxene in elderly persons with psychoemotional disorders against a background of initial and moderately pronounced atherosclerotic circulatory encephalopathy]
Lik Sprava. 1995 Jul-Aug;(7-8):29-32. Russian.
PMID: 8846366 [PubMed - indexed for MEDLINE]
15: Trovato GM, Catalano D, Carpinteri G, Runcio N, Mazzone O. Related Articles, Links
Effects of lactitol [correction of lactilol] on hepatic encephalopathy and plasma amino-acid imbalance.
Recenti Prog Med. 1995 Jul-Aug;86(7-8):299-303.
PMID: 7569287 [PubMed - indexed for MEDLINE]
16: Daga MK, Sarin K, Sarkar R. Related Articles, Links
A study of culture positive multidrug resistant enteric fever--changing pattern and emerging resistance to ciprofloxacin.
J Assoc Physicians India. 1994 Aug;42(8):599-600.
PMID: 7868549 [PubMed - indexed for MEDLINE]
17: Ishchenko MM, Korol'kov AS. Related Articles, Links
[The effect of pentoxifylline on the systemic and cerebral hemodynamics in patients with circulatory encephalopathy and an atherosclerotic lesion of the precerebral arteries]
Lik Sprava. 1994 May-Jun;(5-6):144-6. Russian.
PMID: 7831883 [PubMed - indexed for MEDLINE]
18: Langley PG, Hughes RD, Forbes A, Keays R, Williams R. Related Articles, Links
Controlled trial of antithrombin III supplementation in fulminant hepatic failure.
J Hepatol. 1993 Mar;17(3):326-31.
PMID: 8315261 [PubMed - indexed for MEDLINE]
19: Lepakhin VK, Ivleva AIa, Romashova MF, Udotova SA, Zubovskii LG. Related Articles, Links
[The effect of isradipine on the central and cerebral hemodynamics of patients with circulatory encephalopathy and hypertension]
Eksp Klin Farmakol. 1992 Nov-Dec;55(6):24-6. Russian.
PMID: 1305868 [PubMed - indexed for MEDLINE]
20: Ishchenko MM, Shkrobot SI. Related Articles, Links
[The effect of nicergoline on the systemic and cerebral hemodynamics of patients with circulatory encephalopathy and an atherosclerotic lesion of the major cerebral arteries]
Lik Sprava. 1992 Oct;(10):100-2. Russian.
PMID: 1485425 [PubMed - indexed for MEDLINE]
21: Burtsev EM, Savkov VS, Shprakh VV, Burtsev ME. Related Articles, Links
[10-year experience with using Cavinton in cerebrovascular disorders]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1992;92(1):56-60. Russian.
PMID: 1319651 [PubMed - indexed for MEDLINE]
22: Vesel'skii ISh, Sanik AV. Related Articles, Links
[The correction of microcirculatory disorders in patients with circulatory encephalopathy]
Vrach Delo. 1991 Jul;(7):85-7. Russian.
PMID: 1771847 [PubMed - indexed for MEDLINE]
23: Voloshin PV, Iavorskaia VA, Malakhov VA. Related Articles, Links
[The drug correction of disorders in the erythrocyte structural-functional properties of patients with atherosclerotic circulatory encephalopathy]
Vrach Delo. 1991 Apr;(4):59-62. Russian. No abstract available.
PMID: 2063570 [PubMed - indexed for MEDLINE]
24: Vesel'skii ISh, Sanik AV. Related Articles, Links
[Microcirculation and the blood rheological properties and their correction in ischemic disorders of the cerebral circulation]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(11):67-70. Russian.
PMID: 1666230 [PubMed - indexed for MEDLINE]
25: Lebedeva NV, Khrapova EV, Fedorova TN. Related Articles, Links
[Effect of a new Soviet-made antioxidant on the processes of lipid peroxidation in the treatment of patients with transient cerebro- vascular diseases and circulatory encephalopathy]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1991;91(7):79-82. Russian.
PMID: 1661491 [PubMed - indexed for MEDLINE]
26: Ishchenko MM, Ostrovskaia OS. Related Articles, Links
[The effect of combined drug treatment on rheologic properties of the blood in patients with disordered circulatory encephalopathy]
Vrach Delo. 1990 Mar;(3):58-60. Russian.
PMID: 2368364 [PubMed - indexed for MEDLINE]
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