Спасибо - висит свободная копия
там СТАТИСТИЧЕСКИ значимые различия в пределах нормы - а кому как не Вам знать все пробелмы нормы у детей
Так что я присоединяюсь к Валентину Викторовичу - не стоит это размышлений

he 246 obese children demonstrated significantly higher concentrations of TSH [median 2.4 (interquartile range, IQR, 1.8–3.2) mIU/liter, P = 0.009] and fT3 [median 4.2 (IQR 3.8–4.7) pg/ml, P = 0.003] compared with the 71 nonobese children [median TSH 2.2 (IQR 1.6–2.7) mIU/liter, median fT3 3.9 (IQR 3.5–4.4) pg/ml], whereas fT4 concentrations did not differ significantly [median 1.2 (IQR 1.1–1.4) ng/dl vs. median 1.2 (IQR 1.1–1.3) ng/dl, P = 0.804]. The obese children did not differ significantly in respect of age [median 10.4 (IQR 8.5–12.0) yr vs. median 11.1 (IQR 8.7–12.9) yr, P = 0.332], sex (55 vs. 58% girls, P = 0.713), and pubertal stage (55 vs. 49% prepubertal, P = 0.197) from the nonobese children. No child had a goiter, thyroidal autoantibodies, or clinical signs of hyperthyroidism or hypothyroidism.

In the multiple regression analyses adjusted for age, gender, pubertal stage, degree of overweight, and insulin resistance index (HOMA) of the 246 obese children, there were no significant correlations between TSH and HDL (P = 0.199), LDL (P = 0.298), and total cholesterol (P = 0.939), between fT3 and HDL (P = 0.183), LDL (P = 0.935), and total cholesterol (P = 0.722), as well as between fT4 and HDL (P = 0.199), LDL (P = 0.088), and total cholesterol (P = 0.394).

Forty-three obese children (17%) demonstrated TSH concentrations more than 97.5th percentile (TSH > 3.55 mU/liter). The fT3 and fT4 concentrations of these children were within the normal range (n = 38) or more than 97.5th percentile (fT3 > 5.3 pg/ml; n = 5). The children with TSH concentrations more than 3.55 mIU/liter did not differ significantly in their fT3, fT4, and lipid concentrations, or in age, gender, and degree of overweight from the children with TSH levels less than or equal to 3.55 mIU/liter (see Table 1).