Отменить, говорите, атенолол до операции?
. Смотрите Beta-Blocker Therapy in Noncardiac Surgery
Don Poldermans, M.D., and Eric Boersma, Ph.D.
In a placebo-controlled trial involving 200 high-risk patients, Mangano et al. found that atenolol (50 or 100 mg), administered intravenously beginning 30 minutes before surgery and then orally throughout hospitalization, did not lower the risk of death from cardiac causes or myocardial infarction during hospitalization.5 However, it did result in a 50 percent reduction in myocardial ischemia, as assessed by continuous 48-hour Holter monitoring.
The DECREASE study (Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography), involving a high-risk population of 112 patients who were undergoing vascular surgery, showed that the rate of perioperative death from cardiac causes and myocardial infarction among patients who were randomly assigned to bisoprolol therapy (5 or 10 mg) started at least 30 days before surgery was 90 percent lower than that among patients assigned to standard care (3.4 percent vs. 34 percent).6 In a meta-analysis of six randomized trials involving 694 surgical patients, beta-blockers were associated with a 75 percent reduction in the risk of perioperative death from cardiac causes.7
И т.д., таких публикаций - масса, я как-то собирал. У буржуинов есть Valerie A. Palda, Allan S. Detsky. Clinical Guideline, Part II. Perioperative Assessment and Management of Risk from Coronary Artery Disease. Ann Intern Med 1997;127:313—28.
Правда, это не совсем про гипотензиву, но полезно.