[Dr.Vad]

В отличие от лекарств для общей анестезии, IgE-опосредованная аллергическая реакция на именно лекарства для местной анестезии - скорее нон-сенс:

It is not unusual for patients to claim they are allergic to local anesthetics. Upon careful questioning, however, one generally finds that what they experienced was either a syncopal episode associated with the injection or cardiac palpitations attributed to epinephrine either contained in the solution or released endogenously. Although rare, reports of allergic reactions to local anesthetics have appeared in scientific literature, but none of these have confirmed an IgE-mediated hypersensitivity reaction.

хотя бывает на некоторые соединения и консерванты, находящиеся в ампуле или инжекторе:

Nevertheless, patients have occasionally experienced symptoms consistent with an allergic reaction to amide local anesthetics. In some cases, these episodes have been attributed to preservatives (methylparaben) or antioxidants (bisulfites) contained in the solution.

Алгоритм выяснения природы реакций при проведении местной анестезии, которые напоминают аллергическую: [Ссылки доступны только зарегистрированным пользователям ]