А только совсем недавно в ред. комментарии клеймили его еще позором:
The benefit of coenzyme Q10 supplements in the management of chronic heart failure: a long tale of promise in the continued absence of clear evidence.
Stocker R, Macdonald P.
Am J Clin Nutr. 2013 Feb;97(2):233-4.
в ответ на данные мета-анализа:
Supplementation with CoQ10 resulted in a pooled mean net change of 3.67% (95% CI: 1.60%, 5.74%) in the EF and -0.30 (95% CI: -0.66, 0.06) in the NYHA functional class. Subgroup analyses showed significant improvement in EF for crossover trials, trials with treatment duration ≤12 wk in length, studies published before 1994, and studies with a dose ≤100 mg CoQ10/d and in patients with less severe CHF. These subgroup analyses should be interpreted cautiously because of the small number of studies and patients included in each subgroup.
CONCLUSIONS: Pooled analyses of available randomized controlled trials suggest that CoQ10 may improve the EF in patients with CHF.
Am J Clin Nutr. 2013 Feb;97(2):268-75.
Effect of coenzyme Q10 supplementation on heart failure: a meta-analysis.
Fotino AD, Thompson-Paul AM, Bazzano LA.
Department of Medicine, School of Medicine, Tulane University, New Orleans, LA 70112, USA
Интересно, что доза Q10 была 300 мг, можно ли это экстраполировать на прием 100 или 200 мг препарата?
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