[rsp]

Впрочем некоторые тенденции по подгруппам были озвучены P.Serruys на европейском митинге кардио-торакальных хирургов в Лиссабоне:

Serruys also presented a subanalysis of the new results by SYNTAX score. "Subgroups have been criticized, but they are useful to dissect," he observed. He reminded attendees that the "original goal of the SYNTAX score was to provide guidance on optimal and detailed analysis of the coronary angiography anatomy; it was not yet a prognostic code."

Subgroups have been criticized, but they are useful to dissect.
Now, at four years, there is no difference in MACCE between CABG and PCI in those with a SYNTAX score of 0 to 22, he noted (26.1% vs 28.6%; p=0.57). This is "pretty good," he said, "and would legitimize the use of PCI in this kind of patient."

But for those with an intermediate SYNTAX score of 23 to 32, "you see immediately a highly significant difference" in MACCE rate (21.5% for CABG vs 32% for PCI; p=0.006). And for those with a high SYNTAX score (>33), "mortality is double in the PCI group compared with CABG (16.1% vs 8.4%; p=0.04) and MI is two to three times higher with PCI than with CABG (9.3% vs 3.9%; p=0.01)," he observed.

In this highest-risk group, even the end point of death/stroke/MI becomes significantly higher with PCI, Serruys added (22.7% vs 14.6%; p=0.01), and MACCE were much higher (40.1% vs 23.6%; p<0.001), driven in large part by a 17% higher rate of revascularization in this high-risk group at four years.