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#1
04.08.2011, 09:01
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Ìåäèöèíñêèå ññûëêè ïî ëàáîðàòîðíîé äèàãíîñòèêå.
[Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
Correction Factor for CSF Protein Levels in Traumatic Lumbar PunctureSubtract 1.1 mg/dL protein for every 1000-cell increase in CSF red blood cell count. Traumatic lumbar puncture (LP) is common in children and occurs when the needle causes bleeding into the subarachnoid space. Introduction of peripheral red blood cells (RBCs) in cerebrospinal fluid (CSF) increases CSF protein levels, thereby complicating diagnosis of bacterial meningitis. Investigators examined the association between CSF RBC count and CSF protein level in a prospective cohort of 1298 patients (median age, 3 months; age range, 0 days –23 years) who underwent LP in the emergency department at a children's hospital in Boston and did not have evidence of meningitis. Most LPs were performed to evaluate for possible meningitis. Overall, 189 patients (15%) had traumatic LPs (CSF RBC count >1000/mm3). CSF protein level increased by 1.1 mg/dL for every 1000-cell increase in CSF RBC count. A similar linear relation between CSF RBC count and protein levels was observed in subgroups of patients without pleocytosis, patients with traumatic LP, and patients who were younger than 90 days. Children with traumatic LP were significantly more likely to be admitted than those with nontraumatic LP. Comment: As many as 30% of LPs in children are traumatic and lead to uncertain interpretation of CSF protein concentrations. This study identified a correction factor for interpreting CSF protein levels after traumatic LP. If the results are validated, use of this correction factor might prevent unnecessary hospitalizations. The relation between CSF red blood cell count and white blood cell count was not studied. — F. Bruder Stapleton, MD Published in Journal Watch Pediatrics and Adolescent Medicine August 3, 2011 [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] (Free) 
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#2
05.08.2011, 13:30
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Íîâîå â äèàãíîñòèêå èíôàðêòà ìèîêàðäà - êîïåïòèí
[Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
Recommendations 1.1 The BRAHMS copeptin assay shows potential to reduce the time taken to rule out myocardial infarction in patients presenting with acute chest pain, when used in combination with cardiac troponin testing. However there is currently insufficient evidence on its use in clinical practice to support the case for routine adoption of the BRAHMS copeptin assay in the NHS. 1.2 Research is recommended in the UK clinical setting to compare the BRAHMS copeptin assay in combination with cardiac troponin testing against sequential cardiac troponin testing for ruling out myocardial infarction. NICE will review this guidance when new and substantive evidence becomes available. 1.3 Research should document what happens to all patients presenting with acute chest pain in the chosen clinical settings, to allow investigation of the proportion of patients for whom use of the BRAHMS copeptin assay results in changes in management. Accurate recording of the times between steps in management will be important. Outcomes should measure the resource use implications of the earlier ruling out of myocardial infarction, and the impact this has on decisions to discharge patients from hospital or to investigate them further. Changes in the experience of patients as a result of using the BRAHMS copeptin assay should also be reported.
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#3
09.08.2011, 19:28
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Êàçàëîñü áû ÷òî îáùåãî ìåæäó ëàáîðàòîðíîé äèàãíîñòèêîé è âàìïèðèçìîì?
 Diagnostic Blood Loss From Phlebotomy and Hospital-Acquired Anemia During Acute Myocardial Infarction Blood Loss from Hospital Lab Tests Leads to Anemia in MI Patients [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#4
18.08.2011, 17:04
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Íîâîå â äèàãíîñòèêå ïðåäàíåìè÷åñêîãî/ëàòåíòíîãî æåëåçîäåôèöèòà: ðàñòâîðèìûé ðåöåïòîð òðàíñôåððèíà
J Gastrointestin Liver Dis. 2009 Sep;18(3):345-52. Soluble transferrin receptors and iron deficiency, a step beyond ferritin. A systematic review. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Serum transferrin receptor and transferrin receptor-ferritin index identify healthy subjects with subclinical iron deficits. Suominen P, Punnonen K, Rajamäki A, Irjala K. Blood. 1998 Oct 15;92(8):2934-9. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#5
07.05.2012, 19:37
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Ìàòåðèàëû 2011 Convocation of Experts on Laboratory Quality
International Experts in Laboratory Quality gathered in Salzburg, Austria April 4-6 2011, to discuss the difficult challenges facing our laboratories, and to provide advanced ideas on how to overcome those challenges. This series of videos allows experienced and non-experienced laboratory professionals across the world to learn the latest thinking on critical laboratory concepts.
The event took place over 3 days. Videos are either from Day 1 (Topic introduction) or Day 3 (Reporting the Outcomes of the working groups). Day 1 presentations include the use of interactive polling devices to get real-time feedback from the audience. Day 3 presentations were simultaneously broadcast of the internet as a live Webinar on April 6. The keynote lecture, "Towards a New Paradigm in Managing Risk in the Clinical Laboratory", was delivered by Dr. James Nichols of the USA. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#7
26.11.2012, 16:44
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Êàêàÿ ïðåëåñòü. Ðåáÿòà êîëåñÿò ïî âñåìó ìèðó îò Áðàçèëèè äî Âîñòî÷íîãî Òèìîðà è Àâñòðàëèè è íà ìåñòå çàíèìàþòñÿ ÏÖÐ äèàãíîñòèêîé èíôåêöèé. Âñå îáîðóäîâàíèå çàíèìàåò 5 êîðîáîê è âåñèò 50 êã.
[Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#8
14.12.2012, 19:05
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Pearls and Pitfalls in the Hematology Lab
Clotting and Bleeding
H. Rand and Lucia R. Wolgast Dos and don'ts in diagnosing antiphospholipid syndrome Hematology 2012 2012:455-459; [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Dorothy M. (Adcock) Funk Coagulation assays and anticoagulant monitoring Hematology 2012 2012:460-465; [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Teresa Quiroga andDiego Mezzano Is my patient a bleeder? A diagnostic framework for mild bleeding disorders Hematology 2012 2012:466-474; [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Updates on Cellular Diagnostics Tracy I. George Malignant or benign leukocytosis Hematology 2012 2012:475-484; [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Peter Valent Low blood counts: immune mediated, idiopathic, or myelodysplasia Hematology 2012 2012:485-491; [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Ralph Green Anemias beyond B12 and iron deficiency: the buzz about other B's, elementary, and nonelementary problems Hematology 2012 2012:492-498; [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#9
08.04.2013, 17:59
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Âîçìîæíîñòè àâòîàíàëèçàòîðîâ â ýòîì íàïðàâëåíèè îò ðàçëè÷íûõ âåäóùèõ ïðîèçâîäèòåëåé:
Biomarkers of Hypochromia: The Contemporary Assessment of Iron Status and Erythropoiesis [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#10
12.04.2013, 17:47
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Áðèòàíñêèé ãàéä ïî ïðèíöèïàì äèàãíîñòèêè ôóíêöèîíàëüíîãî (ëàòåíòíîãî) æåëåçîäåôèöèòà:
Guideline for the laboratory diagnosis of functional iron deficiency. Thomas DW, Hinchliffe RF, Briggs C, Macdougall IC, Littlewood T, Cavill I; British Committee for Standards in Haematology. Br J Haematol. 2013 Apr 10. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#11
14.05.2013, 20:15
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Áûë íà ìåæäóíàðîäíîé êîíôåðåíöèè ïî ëàá. ãåìàòîëîãèè, âñå ñëàéä-ïðåçåíòàöèè âûëîæåíû çäåñü:
[Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] òàêæå òåêñòû ê íåêîòîðûì èç íèõ â äàííîì îáó÷àþùåì ìàòåðèàëå: International Journal of Laboratory Hematology [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#12
17.05.2013, 21:23
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Lab Medicine
Ñîâñåì íåäàâíî îòêðûë äëÿ ñåáÿ æóðíàë, êîòîðûé íàçûâàåòñÿ Lab Medicine:
[Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] ïðåëåñòü - ïóáëèêàöèè ñòàðøå 1 ãîäà, äîñòóïíû â ïîëíîé âåðñèè, ìèíóñû - íå èíäåêñèðóåòñÿ â ïàáìåäå, à çíà÷èò íå íàéòè îïóáëèêîâàííûå òåìàòè÷åñòèå ñòàòüè è îáçîðû, åñëè íå âîéòè â ïîèñêîâèê æóðíàëà
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#13
17.05.2013, 23:23
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PS. êàê ïðèìåð îòòóäà:
Benie T. Constantino Pelger-Huët Anomaly—Morphology, Mechanism, and Significance in the Peripheral Blood Film Lab Med 2005 36:103-107 [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#14
22.05.2013, 22:45
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Èíòåðåñíàÿ ñòàòüÿ â ïîëíîé âåðñèè â íîâîì æóðíàëå, îòäåëüíàÿ ãëàâà (â êîíöå), êàê îïðåäåëÿòü èñòèííûå öèôðû ôåððèòèíà ïðè âîñïàëåíèè, ÷òîáû çàïîäîçðèòü/èñêëþ÷èòü äåôèöèò æåëåçà ïðè ëîæíîïîâûøåííîì ôåððèòèíå.
J Blood Med. 2013 Mar 20;4:11-22. Biomarkers for the differentiation of anemia and their clinical usefulness. Northrop-Clewes CA, Thurnham DI. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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#15
25.10.2013, 22:42
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spurious results on haematology analysers
Int J Lab Hematol. 2007 Feb;29(1):4-20.
Spurious counts and spurious results on haematology analysers: a review. Part I: platelets. [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ] Int J Lab Hematol. 2007 Feb;29(1):21-41. Spurious counts and spurious results on haematology analysers: a review. Part II: white blood cells, red blood cells, haemoglobin, red cell indices and reticulocytes. Zandecki M, Genevieve F, Gerard J, Godon A. Haematology Laboratory, University Hospital of Angers, Angers, France [Ññûëêè äîñòóïíû òîëüêî çàðåãèñòðèðîâàííûì ïîëüçîâàòåëÿì ]
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Ëèíåéíûé âèä
