Цитата:
The study looked at a cohort from the National Inpatient Sample, 33,343 patients who were admitted to the hospital for takotsubo syndrome from 2003 to 2011; of these, 210 patients were active marijuana users, as indicated by patient history or a positive urine drug screening test.
The marijuana users formed a distinct subgroup of takotsubo patients. A total of 64% of the marijuana users were women and 36% were men, whereas 92% of the nonusers were women and 8% were men.
Compared with patients who did not use marijuana, active users were younger and had a lower prevalence of hypertension (38% vs 62%), type 2 diabetes (2.4% vs 17.6%), and hyperlipidemia (15.7% vs 52.4%; all P<0.001).
However, the active users were also more likely to have psychiatric illness or abuse substances. Specifically, they were more likely to have a history of depression (32.9% vs 14.5%), anxiety disorder (28.4% vs 16.2%), or psychosis (11.9% vs 3.8%), and they were more likely to smoke (73.3% vs 28.6%) or abuse alcohol (13.3% vs 2.8%) or cocaine or amphetamines (11.9% vs 0.3%; all P<0.001).
In multivariable binary regression analysis adjusted for known risk factors for takotsubo, marijuana use was an independent predictor of takotsubo (odds ratio 1.99, 95% CI 1.72–2.32; P<0.0001).].
Patients who used marijuana were less likely to die during hospitalization (0% vs 1%, P=NS) and less likely to have a major adverse cardiac event (23% vs 32%, P=0.008).
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Но мне больше понравилось как высказался один из исследователей:
Цитата:
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"We need to understand more about the potential association between marijuana use and cardiovascular adverse events and continue to investigate the mechanisms that might explain it"
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References:
Singh A, Agrawal S, Fegley M, et al. Marijuana (cannabis) use is an independent predictor of stress cardiomyopathy in younger men.. American Heart Association 2016 Scientific Sessions; November 13, 2016; New Orleans, LA. Abstract S4054