[Dr.Vad]

TB in children is of major importance to the Russian TB program. Use of a newly developed skin test based on recombinant proteins containing ESAT6 and CFP10 antigens (Diaskintest; CJSC Generium, Russia–Switzerland) led to improvements in TB diagnosis in pilot studies of children. Pilot studies demonstrated 95% concordance of Diaskintest and IFN-γ release assay (QuantiFERON-TB Gold) and greater specificity of both tests compared with Mantoux 2TU (purified tuberculin PPD, Manufacturing enterprise of the Institute for Vaccines and Serums, Saint-Petersburg, Russia) (26).

Tuberculosis in Russia. Its History and Its Status Today
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