В приведенной вами статье от 1998 года написано следуюшее:
Цитата:
Consequences of iodine excess
Tolerance to iodine is highly variable. Most people can be exposed to large amounts without apparent problems (9). Important exceptions to this statement are preexisting iodine deficiency, autoimmune thyroid disease, and papillary cancer. In communities where recent iodine deficiency has been rapidly corrected, iodine-induced hyperthyroidism is a predictable event (10). It occurred in the United States in the early part of this century and is now showing up in many other countries as they become iodine sufficient. The principal victims are older subjects with autonomous nodules because they are unable to regulate the newly available iodine properly, and instead produce excessive thyroid hormone. The frequency and complications of iodine-induced hyperthyroidism are heightened by poor monitoring of salt iodine concentration, which permits high and uneven rations of iodine, and also by inadequate medical attention, which delays diagnosis and treatment. Without trivializing its seriousness, most observers agree that the risk of iodine-induced hyperthyroidism should not obscure the many benefits that iodine sufficiency has for women and children, and should not slow the pace toward proper correction of the deficiency in a community (3).
Iodine intake appears causally related to autoimmune thyroid disease (9). Injection of thyroglobulin into experimental animals induces a thyroiditis similar to human autoimmune thyroiditis, and the immunological response is more vigorous with iodine-rich thyroglobulin (11). Administration of iodine to goitrous humans provoked a reversible thyroiditis and antibody elevation in some (12). Epidemiological studies have shown that an increased incidence of autoimmune thyroid disease frequently parallels an increased dietary iodine intake (13).
The amount of dietary iodine also influences the type and incidence of thyroid cancer. In experimental work with rats and mice, iodine deficiency is associated with the appearance of both papillary and follicular cancer. In areas that corrected previously established iodine deficiency (e.g. Argentina and Austria), the incidence of papillary thyroid cancer increased, whereas that of follicular cancer decreased (13). Epidemiological studies show a general correlation of dietary iodine with the presence of occult papillary cancer, ranging from 9% on autopsies in iodine-deficient Poland to 36% in iodine-enriched Finland (14).
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