вот тезисы статьи 35 летней давности, когда взрослых лечили джозамицином от пневмоний - побочное действие было в 12% и у одного пришлось отменять из-за тошноты рвоты:
Adverse events considered probably to relate to therapy were experienced by 2% of patients treated with clarithromycin and by 12.5% of those treated with josamycin; one patient treated with josamycin was withdrawn because of severe nausea and moderate vomiting. Treatment with clarithromycin at half the dosage of josamycin was found to have comparable efficacy and to be associated with a lower incidence of adverse events.
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