Цитата:
Сообщение от Gilarov
Соталол при низкой фракции противопоказан вроде как...
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Скорее не противопоказан, а не показан для профилактики приступов мерцательной аритмии. В данном случае речь идет о снижение количества ЖЭC и профилактики ВСС.
Европейское руководство по ЖТ 2006 года
8. VENTRICULAR ARRHYTHMIA AND SUDDEN
CARDIAC DEATH RELATED TO SPECIFIC PATHOLOGY
Class IIa
Sotalol is reasonable therapy to reduce symptoms
resulting from VT for patients with LV dysfunction
due to prior MI unresponsive to beta-blocking
agents. (Level of Evidence: C)
Adjunctive therapies to the ICD, including catheter
ablation or surgical resection, and pharmacological
therapy with agents such as amiodarone or
sotalol are reasonable to improve symptoms due to
frequent episodes of sustained VT or VF in patients
with LV dysfunction due to prior MI. (Level
of Evidence: C)
FDA пишет [
Ссылки доступны только зарегистрированным пользователям ]
As with all beta-blockers, caution is advised when initiating therapy in patients with any evidence of left ventricular dysfunction.
и contraindications: uncontrolled congestive heart failure