[angio]

Сообщение от Proxor

Попалась книга 2003 года издания Interventional cardiology secrets (E. Marchena, A. Ferreira) построенна, как и все книги из этой серии в виде вопросов и ответов. Цитирую дословно:
13. What are the proposed therapies for no reflow?
Pharmacologic agents:
-Anecdotal reports have shown normalization of flow with intracoronary (IC) administration of papaverine, adenosine, nicorandil, verapamil, and systemic abciximab.
-Intracoronary sodium nitroprusside (direct nitric oxide donor) at dose of 50 to 1000 µg is one of most effective therapies for no reflow.
-Rapide high-velocity IC delivery of adenosine boluses using small syringes (3 ml) at doses of 24 to 48 µg improved TIMI flow in SVG-related no reflow.
-IC verapamil (500 µg) bolus injections
-GP IIb/IIIa failed to provide microvascular protection in patients with SVG disease (in the EPIC and EPILOG studies) and, therefore, may not be an effective therapeutic agent when used alone.
Distal protection devices: In the recent multicenter randomized SAFER trial, using the Percusurge system for protection from distal embolization i SVGs, no reflow was reduced from 8.0% to 3.4%. Current studies are underway to determine if the device can be used in other clinical situations such as acute MI and in native coronaries.

Скажите, пожалуйста, кто-нибудь использует нифедипин (Адалат) для лечения no(slow)-reflow??????

Аналогичный вопрос про аденозин. Говорят, что его нет на фарм.рынке, тогда откуда аденозин в ЭФИ-лабораториях?