"...European guidelines on hypertension management 2009, в нем диуретики не выделены в качестве лидирующего класса. Континент мне кажется в этом вопросе более убедительным..."
Проблема "континента", ИМХО, заключется в неоднородности его подхода к решению самых разнообразных проблем (включая артериальную гипертонию):
Thiazide diuretics in hypertension
An article from the E-Journal of the ESC Council for Cardiology Practice
Vol 8 N°35 2 June 2010
The use of diuretics (and beta-blockers) to treat hypertension has known a dramatic decline since the early 1980’s through to the early 1990s with the introduction of ACE-inhibitors and calcium channel blockers. However, thiazide diuretics are still a first line option to treat arterial hypertension, due to their efficacy and cost-effectiveness profile. We have presented major trials on this subject in this review.
Background
Thiazide Diuretics have been used since the late fifties in the treatment of hypertension and remain one of the most important group of drugs used to reduce blood pressure, due to their efficacy and cost-effectiveness profile.
The use of diuretics (and beta-blockers) to treat hypertension has known a dramatic decline since the early 1980’s through to the early 1990s with the introduction of ACE-inhibitors and calcium channel blockers. Thiazides were used in much higher doses then and concerns were raised regarding their metabolic effects (1).
Nevertheless, in this review we will try to demonstrate that thiazide diuretics are still a first line option to treat arterial hypertension....
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